Wednesday 2 May 2012

Fullerenes and Lifespan

A series of interesting studies have started to appear on fullerenes. Life Methyleen Blue, they may possibly act on the electron transport chain, and preferentially accumulate in mitochondria.

However, it is hard to extrapolate data from one fullerene study, and apply it to another - as these studies do not use pristine fullerene, but fullerene with adducts.

There are differences in toxicity and other effects of orders of magnitude with only minor alterations to the adducts.

It appears the fullerene forms a number of adducts as it reacts with olive oil. These appear to be beneficial to the organism - but what their metabolic action is remains unknown.


The first in vivo experiment to show an effect on lifespan is a 2007 study on mice:


This was followed up by a small toxicology study, which also showed lifespan extension effects, at very low dosages of oil-solution of fullerene.

Toxicity appears to be low.


Related Articles:
What happens to fullerene in an oil solution? http://144.206.159.178/ft/145/20269/365615.pdf


General research overview